Long-term outcome studies of testosterone therapy in older hypogonadal men: waiting for Godot?
نویسندگان
چکیده
منابع مشابه
Long-term substitution therapy of hypogonadal men with transscrotal testosterone over 7-10 years.
OBJECTIVE Testosterone (T) substitution of hypogonadal men by conventional intramuscular injection of T esters is not considered optimal because it induces unphysiologically fluctuating serum T levels. In contrast, scrotal T patches produce normal serum (T) levels mimicking diurnal variations. In order to assess the quality of this new form of T substitution we followed hypogonadal men treated ...
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AIM The goal of this study was to determine if long-term testosterone (T) therapy in men with hypogonadism, henceforth referred to as testosterone deficiency (TD), ameliorates or improves metabolic syndrome (MetS) components. METHODS We performed a cumulative registry study of 255 men, aged between 33 and 69 years (mean 58.02 ± 6.30) with subnormal plasma total T levels (mean: 9.93 ± 1.38; ra...
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this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...
Long -Term Outcome Therapy of Toxic Diffuse Goiter in Tehran
SUMMARY In order to evaluate the long-ter m effects of antithyroids and ahlative therapy on patients with toxic diffuse goiter (TDG) in an iodine deficient region, 206 patients were studied in Tehran. Hyperthyroidism recurred in 50%, of 80 patients treated with Methimazole (MMI), from one week to 48 months after cessation of therapy. Another 40 patients remained in remission. Of 102 patients t...
متن کاملExperience with transdermal testosterone replacement therapy for hypogonadal men.
BACKGROUND None of the existing options for long-term testosterone replacement therapy (TRT) for hypogonadal men are ideal. Depot replacement at frequent intervals and implants are effective but invasive and inconvenient for the patient. Oral therapy results in poor hormone levels. Both are associated with undesirable metabolic changes. A transdermal formulation therefore represents a potential...
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ژورنال
عنوان ژورنال: Nature Clinical Practice Endocrinology & Metabolism
سال: 2008
ISSN: 1745-8366,1745-8374
DOI: 10.1038/ncpendmet1002